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怎样治疗脂溢性

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如何治疗脂溢性配图,仅供参考

4. Treatments for Alopecia
Several drugs and treatment strategies were proposed,and some are used to treat hair loss in males and females ).
# Table 1
The common treatment for hair loss .


Hair Loss Type
Treatments



Androgenic alopecia
Topical minoxidil (2 to 5%),oral finasteride/dutasteride,hair transplantation


Alopecia areata
Topical minoxidil (5%),corticosteroids (Topical or oral)


Alopecia totalis
Hair transplantation


Cicatricial alopecia
Topical or oral antibiotics,corticosteroids,scalp reduction surgery,hair transplantation


Senescent alopecia
Topical minoxidil


Traction alopecia
Anti-inflammatory agents,hair transplantation


Telogen effluvium
5-α reductase inhibitors



[Open in a separate window](https://ncbi.nlm.nih.gov/pmc/articles/PMC9963650/table/pharmaceuticals-16-00206-t001/?report=objectonly)
Minoxidil was the first drug approved by the FDA to treat hair loss. Minoxidil might prolong the anagen phase,stimulate and elongate hair follicles,and have antiapoptotic effects . Studies showed that topical minoxidil (2–5%) treatment increases hair count,hair weight,hair shaft diameter,and anagen: telogen ratio . The use of 5% topical minoxidil for 16 weeks significantly improved the hair count in males . Hypertrichosis,scalp itching,and irritation are some side effects of topical minoxidil treatment. After treatment discontinuation,excessive hair will disappear .
Finasteride,an inhibitor of type II 5α reductase,is used to manage and treat male androgenetic alopecia (AGA). Finasteride and 5% topical minoxidil are effective and safe to treat mild to severe AGA; oral finasteride treatment was more efficient . The combination of finasteride and minoxidil treatment significantly improved the hair weight in stump-tail macaque monkeys . Dutasteride is a dual 5α reductase inhibitor and is effective in treating AGA. Dutasteride (2.5 mg/day) treatment was more effective than finasteride (5 mg/day) .
Combination therapy is more effective than a single treatment procedure. Generally,treatment for AGA continues for one year,and the initial signs of progress will appear even after four to six months. The regular use of drugs is necessary to achieve their efficiency in hair regrowth. The drug efficiency and hair regrowth vary depending on the subjects and the intensity of the problem.
Topical minoxidil (2%) showed effective hair regrowth in women with low body mass,whereas cyproterone acetate (50 mg) and Diane treatment were effective in women with hyperandrogenism . Finasteride (2.5 mg) treatment effectively induces hair regrowth in pre- and postmenopausal women .
Hair transplantation is the best option for severe AGA in men,and subsequent 1 mg finasteride treatment helps improve surgery results . However,for women,hair transplantation has complications,and some factors affect that. Surgery may induce an effluvium of the pre-existing hair,and hair thinning is spread over the parietal and occipital regions in women.
Cell therapy is effective for hair loss treatment with mild side effects. Thus,the use of stem cells and follicular cells for hair loss treatment is under development. Dermal sheath cup cells (DSCs) have immune tolerance and hair inductivity,which can be isolated from the peribulbar dermal sheath cup. The DSCs-based treatment for hair regrowth required further improvement. Adipose-derived stem cells and dermal papilla cells (DPCs) are the choices for hair growth therapy. Since hair loss is associated with losing DPCs,improved DPCs-based treatment procedures may promote hair growth .
People are interested in complementary and alternative medicine,especially using natural products to treat hair loss. Hair loss treatment requires a multisensory approach,and natural products may act as adjuvant therapeutic agents to treat hair loss . EGCG,amino acids,caffeine,capsaicin,curcumin,garlic gel,marine proteins,melatonin,onion juice,procyanidin,pumpkin seed oil,red ginseng extract,rosemary oil,saw palmetto,vitamins,and zinc are reported to have beneficial effects in hair regrowth .
However,no concrete treatment procedure is currently available to promote permanent hair growth without side effects.","department":"
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