如何治疗肝病的肝病配图,仅供参考
Treatment of Underlying DiseaseImproving Liver Function
Antiviral treatment with nucleos(t)ide analogues can reduce or eliminate liver inflammation and necrosis,promote the regeneration of liver cells,and help restore the functions of hepatic metabolism and detoxification in chronic liver failure caused by hepatitis B virus.
Artificial Liver Support System
Artificial liver support systems can be divided into three types including non-biological type,biological type and mixed type. The non-biological liver support system is the most widely used type,and consists of hemodialysis,hemofiltration,plasma exchange,blood perfusion,plasma adsorption,and the molecular adsorption recirculation system (MARS) . The artificial liver support system can replace the partial function of the liver,remove the poison accumulated in the body,create conditions that allow for the regeneration of liver cells and provide enough time to wait for liver transplantation for patients with HE. An artificial liver support system can be used to treat acute and chronic HE,but patients with overt stage 2 HE should be especially careful with plasma exchange. Liver transplantation remains the only promising therapy for patients with an acute liver failure or end-stage liver disease.
Liver Transplantation
Liver transplantation is an effective means for all kinds of persistent and severe HE; however,in patients with HE there is a significant increase in mortality among patients awaiting liver transplantation . Recently,it has been reported that cognitive function was not fully recovered after liver transplantation in some patients with severe HE . The key point in improving the prognosis of HE is early recognition and timely treatment. Active treatment should be given when diagnosing covert HE.
Blocking Portosystemic Shunting
Theoretically,for patients with serious PSS,interventional therapy,surgery or permanently/temporarily and partially/totally blocking the PSS can improve the patient’s symptoms. The use of this therapy should be carefully weighed because it can increase the risk of gastrointestinal bleeding in case of portal hypertension.
The Treatment of Covert HE
Covert HE has gained an increasing amount of attention in recent years. Patients with covert HE do not exhibit obvious signs and symptoms; however,their quality of life is reduced because of reduced operational ability or sleep disorders. Without treatment,covert HE will progress to overt HE over time. The population with high risk should be examined and treated early,especially those engaged in potentially dangerous occupations. The following solutions can be referred to: (a) adjusting dietary structure (vegetable protein is the main intake); (b) oral administration of lactulose (15-30 ml,2–3 times daily); (c) oral administration of rifaximin (550 mg,twice a day); (d) oral administration of LOLA (6 g,3 times a day); (e) oral administration of BAAA; and (f) oral administration of probiotic preparations .","department":"