尖锐湿疣的早期如何治疗配图,仅供参考
4. Current TreatmentsThere are currently no well-studied treatments for the human papillomavirus infection. The treatments available target the symptoms and diseases caused by HPV infection such as warts or cancer.
For genital warts,treatments include topical therapies and physical removal or destruction. The topical therapies include imiquimod,podophyllotoxin,sinecatechins,and isotretinoin,with the most commonly used options being imiquimod and podophyllotoxin . The physical removal and destruction treatments include simple surgical excision,liquid nitrogen ablation,electrocauterization,and photodynamic therapy .
The options for treatment of CIN II or III include conization,cryotherapy,and loop electrosurgical excision procedure (LEEP) . For cervical cancer,staging remains important to determine treatment. Due to the significantly higher burden of cervical cancer in LMICs,historically,the staging system for cervical cancer was clinically based. This system allowed countries,particularly LMICs,to better diagnose and stage cervical cancer based on available resources. In 2018,the International Federation of Gynecology and Obstetrics (FIGO) incorporated cross-sectional imaging and pathology into the staging system . Earlier stages may be treated with simple hysterectomy or conization,while later stages may require hysterectomy,radiation,and/or chemotherapy . Chemotherapy has historically been cisplatin-based; however,with an increase in resistance to monotherapy,treatment has been more efficacious when cisplatin-based chemotherapy is combined with another therapy such as topotecan,paclitaxel,5-fluorouracil,or bleomycin . For locally advanced cervical cancer,radiation is often recommended alongside the combined chemotherapy regimen .
As with cervical cancer,anal cancer treatments rely on staging. Local excision is available for small lesions that do not involve sphincters and often do not require further treatment . Patients with more advanced disease require treatment prior to excision,which is commonly radiation and chemotherapy. The most commonly used multimodal approach is local excision followed by mitomycin,5-fluorouracil,and radiation. If the cancer is metastatic,the addition of a cisplatin-based therapy is necessary.
HPV-associated oropharyngeal cancer follows a similar treatment pattern to other HPV-associated cancers . Excision is generally the first treatment and can be completed either with an open procedure or less invasive options of laser and robotic surgery. The standard of care following excision is radiation with cisplatin-based chemotherapy.","department":"
- 上一篇: 怎样治疗强迫症最有效
- 下一篇: 妄想型精神分裂怎样治疗