认知障碍如何治疗配图,仅供参考
Treatment of ManifestationsThe mainstay of treatment for Alzheimer disease (AD) is necessarily supportive and each symptom is managed on an individual basis . In general,affected individuals eventually require assisted living arrangements or care in a nursing home.
Although the exact biochemical basis of AD is not well understood,it is known that deficiencies of the brain cholinergic system and of other neurotransmitters are present. Drugs that increase cholinergic activity by inhibiting acetylcholinesterase produce a modest but useful behavioral or cognitive benefit in some affected individuals. The first such drug was tacrine; however,this agent is also hepatotoxic. Newer such drugs with similar pharmacologic action,such as Aricept? (donepezil) -,Exelon? (rivastigmine),and galantamine -,are not hepatotoxic.
Memantine,an NMDA receptor antagonist,has shown some effectiveness in the treatment of moderate to severe AD - .
Antidepressant medication may improve associated depression.","department":"