药疹怎样治疗

药疹如何治疗配图，仅供参考

Medical Management
The first and foremost medical strategy is identification and cessation of the causative agent,usually the last one the patient initiated 1 to 3 weeks prior to onset of symptoms. Thereafter,treatment is predicated on the severity of the symptoms,both cutaneous and systemic. Corticosteroids are used for both treatment of symptoms and prevention of progression. For milder cases,systemic corticosteroids dosed at 0.5 to 1 mg/kg/day and tapered over 6 to 8 weeks are recommended; for SJS,1 mg/kg/day of prednisolone or 1 to 2 mg/kg/day of methylprednisolone is recommended. Steroid therapy for TEN is reported as both controversial and no longer recommended; if used,it should be within the first 48 hours of treatment because of the increased risk of septic complications with an anti-inflammatory agent. Strict control of blood glucose levels is needed for patients with history of diabetes or on corticosteroids.
For patients with extensive skin involvement,supportive care in an acute burn or intensive care unit is recommended for life support measures,pain management,and prevention of infection. Mechanical ventilation,fluid resuscitation with IV fluids or Ringers solution for electrolyte balance,anticoagulation with heparin to prevent thromboembolism,and supplemental nutrition via a nasogastric tube may be needed in severe cases. Antibiotic therapy is not prophylactic but dependent on clinical symptoms,including positive skin cultures,sudden drop in temperature,or deterioration of patients medical condition. In order to prevent caloric loss and an increase in metabolic rate,a room temperature of 30 ?C to 32 ?C is also recommended.
Clinical studies on the use of intravenous immunoglobulin for patients with SJS and TEN have shown mixed results. Successful treatment appears to be dose dependent (1 g/kg/day for 3 days with a total of 3 g/kg over 3 consecutive days),with early treatment recommended. Other medications that have been studied and found beneficial include IV infliximab,cyclosporine,and IV N-acetylcysteine. Acyclovir has been suggested for herpetic lesions in the oral cavity.","department":"