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支原体怎样治疗

0 新人999 新人999 2025-04-26 14:25 2

支原体如何治疗配图,仅供参考

Treatment of infections
The most difficult question is left to the clinician,who must decide whether a given bacterium,proven on laboratory tests,is pathogenically significant or not.
Ureaplasma and mycoplasma species do not have a cell wall. Beta-lactam antibiotics and vancomycin are thus ineffective. Cyclines (doxycycline,monocycline),josamycin and the fluoroquinolones are effective against the three species known to be pathogenic in the urogenital tract. Tetracyclines and the fluoroquinolones are the first choice antibiotics. In pregnant women in whom these drugs are contraindicated macrolides such as erythromycin are often used.
In addition to the naturally occurring resistances there is increasing acquired antibiotic resistance so that if possible treatment should only begin once the results of antibiotic resistance testing are available.
Current treatment options include:
azithromycin 1 g as a single dose
azithromycin 1,5 g total dose given over 5 days
or doxycycline 100 mg 2 ? daily for 7 days.
Treatment success should be tested three weeks after treatment at the earliest,especially in the case of mycoplasma genitalium. In the presence of bacterial persistence common antibiotic regimes are
metronidazole 500 mg 2 ?/day for 5 – 7 days plus azithromycin for 5 days
or doxycycline for 7 days
or moxifloxacin 400 mg per os 1 ?/day for 7 – 14 days .
Moxifloxacin should be used with caution and only in the context of treatment failure since it can cause a rare but severe liver reaction. Mycoplasma genitalium infection acquired in Southeast Asia is resistant to macrolides and quinolones in 10% of cases and pristinamycin is the only effective antibiotic in these patients .
Treatment of the patientʼs partner with the same antibiotic shown to be effective in the index patient is generally recommended. Condom use or abstinence from sexual intercourse is recommended until symptoms have resolved.","department":"
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