湿疹症如何治疗配图,仅供参考
Treatment of atopic dermatitisPreventive skin hygiene,including barrier-stabilizing topical treatment,hydration,and monitoring and treatment for superinfections are critical in the care of patients with AD. Guidance exists on the treatment of AD in adults and children,and typical treatment strategies for AD include treating visible skin lesions with topical anti-inflammatory medications such as corticosteroids and calcineurin inhibitors in combination with frequently applied emollients to minimize the impact of skin barrier dysfunction.,TCS are an effective first line of anti-inflammatory treatment when applied to skin lesions of patients with AD,and they and are associated with minor side effects.,Steroid-sparing topical agents that are licensed for the treatment of AD include the calcineurin inhibitors tacrolimus ointment and pimecrolimus cream and the phosphodiesterase 4 inhibitor crisaborole; these are preferred for sensitive locations and are used commonly for HND,with narrowband UVB phototherapy as another approved option. Patients with severe AD can also be treated with traditional systemic immunosuppressive medication,such as cyclosporine A or oral glucocorticoids,with off-label use of azathioprine,methotrexate or mycophenolate mofetil sometimes considered. However,use of these systemic immunosuppressants can be limited by their adverse effects and tolerability,particularly for long-term treatment.,Novel biologic therapies include the approved therapy dupilumab,which targets the underlying inflammatory mechanism of AD by selectively blocking type 2 inflammation. – Many novel systemic and topical treatments are also under investigation,including the JAK inhibitors baricitinib,upadacitinib,and abrocitinib,the dual JAK-SYK inhibitor ASN002,as well as antagonists of histamine and TSLP,which are each implicated in the pathogenesis of AD. The implementation and success of these agents in treating AD relies,however,on further elucidation of the various phenotypes and appropriate diagnosis of the disease.","department":"