螺旋杆菌如何治疗配图,仅供参考
Drug treatment for suspected H pylori infectionTreatment for H pylori involves a combination of acidsuppression and antibiotics. This has classically been “triple therapy” a combination of a proton pump inhibitor (PPI) and two separate antibiotics. Currently in Malawi the recommended PPI is omeprazole and the antibiotics are amoxicillin 1g bd and metronidazole 500mg bd. Metronidazole resistance in H. pylori in Malawi was described as being as high as 85% in Lilongwe and therefore patients are given two weeks of therapy rather than the standard seven days suggested by the British National Formulary. It is suspected,though currently not known,that there is a high rate of treatment failure among our patients on this therapy regimen. There are a number of alternatives. Exposure to metronidazole may be high in some sections of our population,and an alternative triple therapy regime that is soetimes effective is omeprazole,amoxicillin and clarithromycin. Higher rates of successful eradication have been described using a “quadruple therapy”,which consists of adding bismuth chelate to the current regime. There have been reports of sequential dosing regimes but most of these make use of more expensive antibiotics not available in Malawi .","department":"